Problem: Establishing of new part in existing production facility with two 2000L production bioreactors. Process requires on-line determination of metabolite and nutrient concentration for cell culture process. Without on-line optimization of media composition is not possible to get harvest and yield of target products.
Solution: Sysbiotech offered to integrate available on market analyzers for on-line determination of components to existing bioreactor system. Using special sampling system we integrate results to controller system with possibility to manage feeding and harvesting strategy.
How it works: Together with customer’s engineers we define which kind of analyzers will be suitable for their application and can be integrated into bioreactor system. After clarification of technical points our engineers start to develop bioreactor system. For easy managing of process and fully use of all features of Sysbiotech SCADA system for cell culture process we integrate new analyzers to our controller. By this way all data generated by analyzers are integrated into the database of Sysbiotech SCADA system. This approach allows customer to use this new numbers for controlling of technological process, reporting and many other possibilities.
Result: Customer got system which is fully made according to their request with integration of all parameters which they need for establishing of profitable process. Before that customer had an experience with lab-scale solution and off-line determination of parameters. But in production scale it was not possible to follow the same strategy with off-line control of such critical parameters as media compositions. Sysbiotech SCADA system allows to make flexible update of the system and integrate new devices into controller system.
Bioreactor for cell culture 2000L